News – Tagged "balm"

What causes the low oral bioavailability of cannabinoids?

by Michael Heller October 13, 2020

What causes the low oral bioavailability of cannabinoids?

Cannabinoids are lipophilic (fat soluble) and have low aqueous solubility [8, 9]. Lipophilic drugs with low solubility, such as cannabinoids often have low oral bioavailability [10]. A deeper look at the body’s digestive system reveals that there is an unstirred water layer (UWL) that lines the gastrointestinal tract (GIT). The UWL acts as a barrier to the absorption of lipophilic materials such as cannabinoids. Thus prior to reaching the absorptive surfaces of the GIT a cannabinoid must become water dispersible allowing it to permeate the UWL. Naturally this process of cannabinoid solubilization is inefficient leading to low oral bioavailability.

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Realize Wellness Social Networks

by Tom Pavlica October 13, 2020

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If I use CBD will I fail a drug test?

by Tom Pavlica October 13, 2020

I get this question quite frequently, here's a quick answer for you... First, it is important to understand your company policies. If you get drug...

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If I use CBD will I fail a drug test?

by Tom Pavlica August 28, 2020

https://www.linkedin.com/pulse/i-use-cbd-fail-drug-test-tom-pavlica/

Posted in analysis, balm, Broad Spectrum, cannabidiol, cannabis, CBD, certificate, COA, cream, dissolvable, drug, follicle, Full Spectrum, hair, hemp, Marijuana, miscible, oil, OTC, over the counter, pee, sample, skin, skincare, soluble, test, tetrahydrocannabinol, THC, tincture, topical, urine, water soluble

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